Novel affinity resin for the purification of the SARS CoV-2 Spike Protein for vaccine development and manufacturing
The result of close work with Navigo Proteins on the ligand development and partnership with Purolite Life Sciences on Praesto® agarose bead technology, the new NGL COVID-19 Spike Protein Affinity Resin from Repligen binds the SARS CoV-2 Spike Protein receptor binding domain (RBD) to yield exceptional purity in a single chromatography step. The product meets all the expected requirements of a high-performance resin, including very high selectivity, high dynamic binding capacities and caustic stability over multi-cycle use.
The resin is available in off-the shelf, pre-packed and pre-qualified OPUS® Columns for rapid implementation as well as in loose resin formats.
NGL COVID-19 Spike Protein Affinity Resin key features include:
NGL COVID-19 Spike Protein Affinity Resin delivers >90% purity in one chromatography step.
SDS-PAGE gel of the SARS-CoV-2 Spike protein Receptor Binding Domain (RBD) expressed in HEK293 cells and purified with NGL COVID-19 Spike Protein Affinity Resin.
The NGL COVID-19 Spike Protein Affinity Resin is available in off-the shelf, pre-packed and pre-qualified OPUS® Columns for rapid GMP implementation as well as in loose resin formats.
OPUS® Columns allow you to progress from development to manufacturing scale in weeks, using pre-packed and pre-qualified chromatography columns.