Realization of PAT inline using variable pathlength spectroscopy - applications in downstream mAbs and viral vector purification

Realization of PAT inline using variable pathlength spectroscopy - applications in downstream mAbs and viral vector purification

The first and only variable pathlength analysis technology has been integrated in-line with flow paths for PAT use in downstream unit operations. Rapid and accurate real-time results were acquired on the widest range of samples and concentrations (from less than 1 mg/mL to over 300 mg/mL), revealing previously unrecognized process characteristics.