UNRIVALED PLUG-AND-PLAY CONFIGURABILITY

Modularity Made Easy with Plug-and-Play Configurability

KrosFlo® KR2i TFF systems achieve an unparalleled combination of configurability and user-simplicity through modular, plug-and-play hardware.  All components, either directly or indirectly, connect to the main pump, which then communicates with the KF Comm 2 software for control and monitoring. 

 UNRIVALED PLUG-AND-PLAY CONFIGURABILITY

More Capabilities, Still Simple.

Get more out of TFF with the flexibility to configure your system to better suit your application needs. Keep your process compact and minimal or expand your capabilities to more advance modes of operation by adding components. Switch back and forth between configurations all without compromising on ease of use.

 

見積を請求

USER-EXPERIENCE WITHOUT GUESSWORK 

Automate, Control and Visualize with KF Comm 2

Control the whole system, configure recipes and automate processes in as little as 4 clicks through the intuitive KF Comm 2 software

  • Conveniently installed on any device using the Windows Operating System 
  • Compatible with Chrome, Mozilla, Firefox and Microsoft Explorer browsers
  • Automatic software and firmware updates
  • Optional 21 CFR Part 11 package available 

 

再生アイコン 動画ポスター

従来のKF Commソフトウェアを使用していますか?    今すぐアップグレード

 USER-EXPERIENCE WITHOUT GUESSWORK

Walk-away automation for your lab

The days of manually adjusting screw clamps are over. A Repligen-exclusive technology, the Automatic Back Pressure (ABV) Valve adds transmembrane pressure (TMP) control to every TFF process, reducing operator hands-on-time, data logging and continuous monitoring while improving process reproducibility. 

  • Automatically adjust tubing pinch distance according to user-defined set-points
  • Maintain uniform TMP throughout process run, decreasing membrane fouling
  • 対応チューブサイズ: 13、14、16、25、HP15、17、HPP24、18、HP35、36、HP36

KrosFlo® KR2i Virtual Demo Series

In this 6-part series, Julie Grace, and Carl Breuning, provide viewers with a virtual training on the KrosFlo® KR2i TFF system. This training series will cover the following topics:

  • Introduction to system components
  • Installation of flow-path and filter
  • KF Comm2 software overview
  • Recipe creation
  • Running a CFC/D/C experiment
  • Recovery of product

 USER-EXPERIENCE WITHOUT GUESSWORK

Standard and Configurable ProConnex® Flow Paths

ProConnex® Flow Paths are customized, configurable and complete assemblies for tangential flow filtration.  Designed for use with hollow fiber and/or flat sheet TFF systems, the assemblies are sterile, fit for upstream or downstream processing and manufactured in compliance with ISO guidelines in an ISO 7 clean room.

ProConnex® Flow Paths       Shop now

 ONE DESIGN, MULTIPLE SYSTEMS

Effortless scaling with a single standardized platform  

Designed as a platform and not as standalone units, KrosFlo KR2i, KMPi, and FS lab scale TFF systems share the same components, software and controls across the entire family, allowing you to confidently standardize your process. Common process change challenges during scale-up are removed.

 

 ONE DESIGN, MULTIPLE SYSTEMS

インラインタンパク質濃度管理が可能なTFF

No longer are you dependent solely on mass inputs and off-line fixed-pathlength UV-Vis spectrophotometers. Now, you can measure what truly matters in real-time with the KrosFlo® KR2i RPM™ System. Monitor concentration in real time during your UF/DF run and control your process. 

Learn more
 

再生アイコン 動画ポスター

System features at a glance

The fully integrated KrosFlo KR2i TFF System features a digital peristaltic pump, graphical LCD display, digital pressure monitor, KR2i Pump head, automatic backpressure valve, filter module stand, and KF Comm real-time data collection software.

Highly configurable and versatile, the KrosFlo KR2i utilizes a number user-defined set-points to run complex application processes with numerous built-in safety alarms and stops. The system can run up to two stackable pump heads for higher flow rates.

Click on the links below to explore different features.

コンポーネントとアクセサリ

  • IP 33エンクロージャー
  • リバーシブルドライブ付き600 RPMポンプ
  • 90-260 Vrms @ 50/60 Hz
  • 精密チューブ用の標準Easy Load 3ポンプヘッド L/S番号13、14、16、25、17、18を提供しています。
  • (オプション)高性能チューブ用Easy Load 3ポンプヘッド L/S番号15、24、35、36
  • ETL(北米安全認証)取得済み、およびCE/UL/cULマーク付き
  • ポンプドライブの寸法: 10.5インチ x 8インチ x 8インチ

KONDUiTは以下を追加します。

  • UF/DFのエンドポイント伝導率制御
  • エンドポイントUV制御で、薬物送達粒子から遊離薬物を透析ろ過
  • エンドポイントUV制御で、特定の分子を濃縮
  • メンブレンブレイクスルー用UVアラーム
  • A260およびA280光源を利用可能

*UVコンポーネントは別売りです

スケール 

TFFプロセスの間、ユーザーが定義した供給重量の設定値と総透過質量を維持します。

今すぐ購入

KrosFlo® KR Jr Auxiliary Pump

補助ポンプは、供給タンクへのバッファーや製品の添加量を自動的に増減させます。

今すぐ購入

トランスデューサー

  • 4つの圧力を測定・表示:供給圧力、保持液圧力、透過圧力、膜間差圧(TMP)
  • ユーザー定義圧力アラームとストップ設定値
  • さまざまなコネクタタイプ(ルアー、TC)および選択した素材(PS、PC)で利用可能

今すぐ購入

Manufacturing Centers of Excellence

Repligenは、ISO 9001品質管理システムに基づいて、バイオ医薬品業界向けの製品を開発・製造しています。高品質で安定した、堅牢な製品をタイムリーに提供し、お客様の事業継続性を保証することを重視しています。

Repligen manufacturing sites are located in Massachusetts, California, and New Jersey in the United States and in Sweden, France, The Netherlands,  Germany and Estonia.

Locations

お客様第一。

サポートは、Repligenという企業の遺伝子に組み込まれています。弊社の目標は、卓越した顧客体験を提供すること、そしてRepligenの製品やサービスの適用や導入を効率よく成功に導くためにサポートすることです。

  • Field Application Support
  • カスタマーサービス
  • フィールドサービスエンジニア

お問い合わせ